Louisville Football Releases 2022 Schedule

Louisville Football’s 2022 schedule has been released! The Cards will have a schedule this year that features 6 true home and road games. Road opponents include Syracuse, UCF, Clemson, Virginia, Boston College, and arch rival Kentucky. Home contests include Florida State, South Florida, James Madison, Wake Forest, Pittsburgh, and NC State.

The Cards first two games will be on the road at Syracuse and UCF. The Cards defeated both of those teams in 2021. The home opener will be against Florida State, whom UofL defeated on the road in 2021. USF then visits Cardinal Stadium before heading back on the road for two games against Boston College and Virginia. The Cards then have a bye before a 3-game home stand against Pittsburgh, Wake Forest, and James Madison. They close out the season with a road contest against Clemson, a home game against NC State, and finally the Battle for the Governor’s Cup against uk.

UofL is looking to improve on its 6-6 2021 regular season record. While the schedule is still tough due to many conference foes returning QBs that really played well against UofL’s defense last season, they also have a much more manageable non-conference schedule with UCF, USF, and James Madison. Winning 8 games is definitely in the realm of possibility for the 2022 Cards.

Below, you can read UofL’s official press release about the schedule.

Press Release From UofL Athletics:

Louisville Football Releases 2022 Schedule 

LOUISVILLE, Ky.—The University of Louisville 12-game football schedule for the 2022 season was released today by the Atlantic Coast Conference.
The Cardinals will host six games at Cardinal Stadium, including four pivotal ACC contests.

The 2022 slate opens with a pair of road contests, including the ACC opener on Sept. 3 versus Syracuse in the Carrier Dome. The Cardinals have won the last three encounters versus the Orange after last season’s 41-3 win at Cardinal Stadium. Louisville hits the road for the second-straight week to face UCF in Orlando on Sept. 10. UofL intercepted pass in the final moments to defeat the Knights 42-35 last year in Louisville. 

The home schedule opens on Friday, Sept. 16 when the Cardinals host Florida State. It will be the first home opener on a Friday since 1960. The Cardinals will remain home to face former Conference USA and BIG EAST rival USF on Sept. 24.

Louisville remains in ACC play with a pair of road contests at Boston College (Oct. 1) and at Virginia (Oct. 8). The Cardinals defeated the Eagles 28-14 last season at home and fell to the Cavaliers 34-33 in the final moments at Cardinal Stadium.

After its lone open week of the season, the Cardinals will host both participants in last season’s ACC title game in Pitt and Wake Forest. The Cardinals will host Pitt for the first time since 2011 when the Panthers visit on Oct. 22. Wake Forest returns to Cardinal Stadium on Oct. 29.

Louisville welcomes James Madison to Cardinal Stadium for the first meeting between the two schools on Nov. 5. The Dukes fell to North Dakota State 20-14 in the FCS Semifinals a year ago.

The Cardinals return to ACC action on Nov. 12 when it travels to Death Valley on Nov. 12 before wrapping up the home season and league play on Nov. 19 versus NC State.

The regular season concludes with a short trip up I-64 to face Kentucky at Kroger Field.

The Cardinals return 18 starters from a year ago after finishing 6-7 last season following a loss to Air Force in the First Responder Bowl.


Sept. 3      at Syracuse*                         Syracuse, N.Y.

Sept. 10    at UCF                                  Orlando, Fla.

Sept. 16    Florida State*                        Louisville, Ky.

Sept. 24    USF                                      Louisville, Ky.

Oct. 1        at Boston College*                 Chestnut Hill, Mass.

Oct. 8        at Virginia*                            Charlottesville, Va.

Oct. 22      Pitt*                                      Louisville, Ky.

Oct. 29      Wake Forest*                        Louisville, Ky.

Nov. 5       James Madison                     Louisville, Ky.

Nov. 12     at Clemson*                          Clemson, S.C.

Nov. 19     NC State*                              Louisville, Ky.

Nov. 26 at Kentucky Lexington, Ky.

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